Iranian state-linked media has identified major US technology companies, including Google, Microsoft, Palantir, IBM, Nvidia, and Oracle, as potential targets due to their connections with Israel and involvement in military applications. The conflict between Iran, Israel, and the United States is beginning to impact the digital infrastructure that supports modern economies.

Anthropic's Claude assisted in selecting hundreds of targets for military strikes in Iran. One of these targets may have been an elementary school where over 100 girls lost their lives.

Anthropic CEO Dario Amodei criticized OpenAI's messaging regarding its military deal with the Department of Defense, labeling it as "straight up lies." Amodei stated that OpenAI accepted the deal to placate employees, while Anthropic prioritized preventing abuses.

President Donald J. Trump criticized Anthropic, calling it a "radical left, woke company" and stated that military decisions should be made by the Commander-in-Chief and appointed leaders. He described Anthropic's actions as a "DISASTROUS MISTAKE."

The U.S. military utilized Anthropic's Claude AI model during the operation to capture Venezuelan leader Nicolás Maduro. Following this use, the Pentagon is reassessing its partnership with Anthropic amid potential backlash.